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TitleDerma Megatable
TagsCutaneous Conditions Acne Vulgaris Herpes Simplex Nail (Anatomy) Psoriasis
File Size143.1 KB
Total Pages21
Document Text Contents
Page 11

LESION AGE OF
PREDILECTION

AREA OF
PREDILECTION

HALLMARK ETIOLOGY PREDISPOSING
FACTORS

TREATMENT OTHER INFO

PSORIASIS

(REVIEW
DIFFERENT

TYPES)

round, circumscribed,
erythematous, dry
scaling plaques of
various sizes, covered
by graying white or
silvery white, imbricated
and lamellar scales

symmetrical, solitary
macule to more than
100 macules

Mean: 27yrs

Wide range (few
months to
seventies)

scalp, nails,
extensor surfaces
of the limbs
(shins), elbows,
knees, umbilical
and sacral region

silvery white,
imbricated and
lamellar scales

oil spots, nail
pitting – nails

patho features:
-abn
differentiation
-keratinocyte
hyperproliferation
-inflammation

Unknown, maybe
hereditary

May disappear
spontaneously, but
almost certain
recurrence

Tx varies accdg to site,
severity, duration, age

Topical
- corticosteroids
- tars
- dihydroxyanthralin
- tazarotene
- vit D
- salicylic acid
- UV
Surgery-denervation
Lasers-destruction of
upper dermis
Systemic
- corticosteroids
- methotrexate
Combination

Koebner’s
Phenomenon:
appearance of
typical lesions at
areas of injuries
(scratches and
burns)

Auspitz’s Sign:
beeding points
secondary to
thinning of the
epidermis over the
dermal papillae

Woronoff Ring:
concentric
blanching of
erythematous skin
near periphery of
healing psoriatic
plaque

Page 20

6 . B U L L O U S D E R M A T O S I S

LESION AGE OF
PREDILECTION

AREA OF
PREDILECTION

HALLMARK ETIOLOGY PREDISPOSING
FACTORS

TREATMENT OTHER INFO

BULLOUS
IMPETIGO

-strikingly large,
fragile bullae

-ruptures & leaves
circinate, weepy or
crusted lesions
(impetigo circinata)

-newborn infants
(4th & 5th days of
life)
-may occur at any
age

-newborn: face &
hands

-adults: axilla,
groin, hands

-Staphylococcus
aureus

-insect bite -systemic
antibiotics

-weakness, fever,
diarrhea with
green stools,
bacteremia,
pneumonia, or
meningitis, fatal
termination

-early
manifestation of
HIV infection

FIXED DRUG
ERUPTION

-begins as an
erythematous
patch that soon
evolves to an iris
or target lesion and
may eventually
blister & erode

-6 or fewer lesions
occur but
frequently single

-prolonged
inflammation
results to
hyperpigmentation

-any age -anywhere but half
occurs on oral &
genital mucosa

-recur at the
same site with
each exposure to
the medication

-medications
usually taken
intermittently
(NSAIDS,
pyrazolone
derivatives,
naproxen,
mefenamic acid,
etc.)

-persons with FDE
to pyrazolone
derivatives are
usually HLA-B22
positive

-stop offending
medication &
replace with
alternative drug

-Nonpigmented
FDR: occurs
occasionally;
characterized by
large, tender,
often symmetrical
erythematous
lesions that
resolves; normally
caused by
pseudoephedrine
hydrochloride

-Baboon
Syndrome:
buttocks, groin &
axilla are
preferentially
involved

Page 21

LESION AGE OF
PREDILECTION

AREA OF
PREDILECTION

HALLMARK ETIOLOGY PREDISPOSING
FACTORS

TREATMENT OTHER INFO

IRRITANT
CONTACT

DERMATITIS

-non-allergic
inflammatory
reaction of the
skin

-erythema
vesicles, erosions,
crusts, scaling

-any age -in areas that has
come in contact
with irritants

-alkalis: soaps,
detergent,
ammonia, lye,
toilet bowl
cleaners

-acids:
hydrofluoric
acids, HCl, nitric,
sulfuric acids

-Ca, Cu, Hg, Ni,
Ag, Br, Cl, Fl, I

-chlorinated
compounds:
Chloracne

-dog collars: Flea
Collar Dermatitis

-capsaicin: Hunan
hand

-condition of skin
upon contact

-skin may be
vulnerable by
reason of
maceration from
excessive humidity
or exposure to
water, heat, cold,
pressure or friction

-alkalis:
immediate
application of a
weak acid
(vinegar, lemon
juice, 0.5% HCl)

-oxalic acids: lime
water

-phenol: 65%
EtOH or isopropyl
alcohol

-fluorine:
magnesium oxide

-periungal burns:
10% calcium
gluconate solution

-phosphorus
burns: rinse with
water & apply
copper sulfate

-titanium HCl:
wipe away, do not
rinse!

ALLERGIC
CONTACT

DERMATITIS

-erythema,
vesicles ,
erosions, crusts,
scaling

-any age -in areas that has
come in contact
with allergen (but
it has to be
previously
sensitized)

-previous exposure
to allergen

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